1897
The Beginning
Hoffmann, a chemist in the pharmaceutical laboratory of the German dye manufacturer Friedrich Bayer & Co in Elberfeld, consulted the chemical literature and came across the synthesis of acetylsalicylic acid and then prepared the first sample of pure acetylsalicylic acid.[18]
1899
Trademark
Aspirin™ is registered as a trademark.[18]
It is launched on the market in powder form.[19]
Just one year later, the analgesic is launched in its classic tablet form – one of the first medicines to be marketed in this dosage form. [20]
1978
Stroke Prevention
A study published in the “New England Journal of Medicine” shows that aspirin can reduce the stroke or death in men. [22]
1982
Nobel Prize
British pharmacologist Sir John Vane was awarded the Noble Prize in Physiology or Medicine for his discovery that the anti-inflammatory properties of aspirin result from its ability to inhibit the body’s production of certain chemical mediators (prostaglandins) that promote inflammation. [23]
1985
Heart Attack Prevention
The US Food and Drug Administration approves aspirin in both the treatment and secondary prevention of acute MI. [19]
Cardiovascular Uses
Indications now include: prevention of strokes after preliminary stages have occurred, and arterial thromboses and prevention of a mayocardial infarction in patients after a high risk was determined by a physician. [1]
1999
Anniversary
Aspirin celebrates the 100th anniversary of its patent. [18]